Graduate Chemistry (CHEM)

The minimum prerequisite for 50000-69999 level courses is graduate standing. The minimum prerequisite for courses 70000 and higher is doctoral standing. Additional prerequisites may apply and are listed in this catalog.

Graduate students in chemistry may not use the following courses to fulfill degree requirements:
5/70000, 5/70093, 5/70361, 5/70362, 5/70481, 5/70555, 5/70556, 5/70557, 5/70558, 5/70570 and 50795.
Non-chemistry majors may take any of these courses for credit with the permission of their major department and the Department of Chemistry and Biochemistry.

50000/70000 Chemical Information (2)
Access to chemical documents using indexes, formulating search strategies, citation mapping and manipulation of  computer files are treated via lectures, readings and library problems. Prerequisite: CHEM 30482.

50093/70093 Variable Title Workshop in Chemistry (1-6)
S/U grading. Prerequisite: special approval.

50112/70112 Advanced Analytical Chemistry (2)
An advanced study of the theory and applications of analytical chemical equilibria: acid base, precipitation, complexation and redox. Prerequisite: CHEM 40555.

50113/70113 Chemical Separations (3)
Theory, instrumentation and applications of chemical separations for chemical analysis with an emphasis on gas and liquid chromatography. Prerequisite: CHEM 30106.

50114/70114 Electroanalytical Chemistry (3)
The physical basis of electrochemistry; instrumentation and applications in chemical analysis. Polarography, coulometry, voltammetry and ion-selective electrodes. Lecture 3 hours weekly. Prerequisite: CHEM 40555.

50245 Biochemical Foundations of Medicine (4)
Introduction to chemistry and metabolism of important compounds in biological systems; enzymes and characteristics of enzyme catalysis; regulation of metabolism at molecular, cellular and organism levels; inborn and induced errors of metabolism. Designed and scheduled for, and priority given to, students in integrated life sciences program. Prerequisite: CHEM 30481.

50248/70248 Advanced Biological Chemistry (3)
Chemistry of biologically important molecules. Advanced topics in: metabolic and enzyme regulation; enzyme kinetics and mechanism; DNA replication, recombination and repair; gene transcription and translation; recombinant DNA technology; selected areas in molecular physiology. Three hours weekly. Prerequisite: CHEM 30284 or CHEM 40245 or CHEM 40247.

50261/70261 Principles of Biochemistry I (3)
Introduction to biochemical principles regarding the structure, function and metabolism of biomolecules including water, amino acids, proteins, carbohydrates and lipids; emphases on enzymes, membranes and bioenergetic. Prerequisite: special approval.

50262/70262 Principles of Biochemistry II (3)
Supramolecular and cellular aspects of biochemistry including DNA replication, repair, recombination and modification; transcription and translation; signal transduction, post-translational modification; transcriptomics and proteomics. Prerequisites: CHEM 50261 or 70261; and special approval.

50263/70263 Physical Biochemistry  I (3)
Principles and techniques of physical chemistry used in studying biomacromolecules and biological systems. Topics covered are thermodynamics, spectroscopy, structure and properties of biological molecules. Prerequisite: CHEM 40555.

50302 Inorganic Chemistry II (3)
Physical techniques in inorganic chemistry, molecular structure and bonding, metallic and ionic solids, organometallic chemistry, homogeneous and heterogeneous catalysis; solidstate and materials chemistry, nanomaterials, nanoscience and nanotechnology. Prerequisite: CHEM 30301.

50303 Inorganic Chemistry III (3)
Molecular symmetry, molecular orbital theory of polyatomic molecules and octahedral complexes, electronic spectra and reaction mechanisms of d-block complexes, periodic trends Groups 1 and 2 and d-block, bioinorganic chemistry. Prerequisite: CHEM 50302.

50352/70352 Inorganic Materials Chemistry (3)
Broad survey of the synthesis, properties, characterization and applications of inorganic materials. 

50365/70365 Biological Inorganic Chemistry (3)
Physical methods, s-block metals, metal-induced stabilization, electron transfer proteins, oxidoreductases, hydrolases and lyases, metal transport and storage, nitrogenases, group-atom transfer and metals in medicine. Prerequisite: CHEM 30360.

50451/70451 Organic Materials Chemistry (3)
Broad survey of the synthesis, properties, characterization and applications of organic and polymeric materials. 

50476/70476 Spectroscopic Identification of Organic Compounds (2)
Strategies for structural elucidation of organic compounds from analysis of infrared, proton and carbon NMR and mass spectrometric data through lectures and problem solving. Prerequisite: CHEM 30482.

50478/70478 Synthesis of Organic Liquid Crystals (3)
Synthesis of organic thermotropic liquid crystals including nematic, smectic and discotic variants. Evaluation of the phase types using polarizing microscopy and DSC. Brief introduction into their use in display devices. Prerequisite: CHEM 30482.

50555/70555 Elementary Physical Chemistry (3)
Fundamental concepts of physical chemistry, with example problems chosen emphasizing application in chemistry and the biological science. Prerequisite: CHEM 10061 and MATH 22005 and PHY 23102. Pre- or corequisite: CHEM 30107.

50556/70556 Elementary Physical Chemistry (3)
A continuation of CHEM 50555. Areas covered are chemical kinetics, quantum chemistry and the solid state. Prerequisite: CHEM 50555 or PHY 45301

50557/70557 Physical Chemistry Laboratory (2)
Experiments in numerous areas of physical chemistry, including the interpretation and reporting of obtained experimental data, correlation of results with theory and an introduction to the computer treatment of data. Pre- or corequisite: CHEM 5/70555. Special course fee: $40 per credit hour (subject to change).

50558/70558 Physical Chemistry Laboratory (2)
Experiments and interpretation, reporting, and correlation of data with theory. Emphasis on gases, liquids, solutions, surface properties, thermodynamic variables, rates of reaction, transport phenomena and spectral properties. Pre- or corequisite: CHEM 5/70556.

50570/70570 Intermediate Physical Chemistry (2)
Special topics of physical chemistry, with applications to problems of chemical interest that are not covered in the basic course. Prerequisite: CHEM 5/70556.

50571/70571 Surface Chemistry (2)
Treatment of basic principles and concepts in surface and colloid chemistry. Relationship to practical systems emphasized. Prerequisite: CHEM 40555 or 40567.

50575/70575 Molecular Spectroscopy (3)
Survey of the fundamental principles of the interaction of radiation with matter, with an emphasis on the interpretation of microwave, infrared and ultraviolet-visible spectra. Introduction to group theory and its application to spectroscopic interpretation. Description of modern experimental techniques. Prerequisite: CHEM 40556.

50583/70583 Physical Chemistry of Macromolecules (2)
A course designed to cover the basic principles of polymer science. Structure, properties and characterization of polymeric systems will be discussed. Prerequisite: CHEM 40555 or 40567.

50795 Current Topics in Chemical Education (1-3)
Designed to present recent advances in chemical research, instrumentation and theory to chemistry educators. S/U grading. Prerequisite: special approval.

60050/70050 Chemistry Research Proposal (3)
The student will prepare an independent and original research proposal that is completely distinct from the thesis project.

60111/70111 Theory of Chemical Instrumentation (2)
General survey course on theory of instruments. Special emphasis on data interpretation and problem solving. Prerequisite: special approval.

60115/70115 Analytical Spectroscopy (3)
An advanced study of the fundamental principles, instrumentation and experimental techniques associated with different analytical spectroscopic methods.

60199 Thesis I (2-6)
Thesis students must register for a total of 6 hours, 2 to 6 hours in single semester, distributed over several semesters if desired. IP permissible.

60249/70249 Biochemical Techniques (2 each)
Laboratory work emphasizing modern methods of biochemical investigation. Experiments illustrating use of spectrophotometric, chromatographic and isotopic methods. May be taken for graduate credit by chemistry majors. S/U grading; IP permissible. Co- or prerequisite: CHEM 60247 or 70247.

60250/70250 Biochemical Techniques (2 each)
Laboratory work emphasizing modern methods of  biochemical investigation. Experiments illustrating use of spectrophotometric, chromatographic and isotopic methods. May be taken for graduate credit by chemistry majors. S/U grading; IP permissible. Co- or prerequisite: CHEM 60249 or 70249.

60265/70265 Enzymology (3)
Basic principles of steadystate and rapid enzyme kinetics; theory and experiment; catalytic mechanisms for selected enzymes. Prerequisite: special approval.

60269/70269 NMR: Theory and Application in Biochemistry (1 or 2)
Basic principles of high-resolution nuclear magnetic resonance will be applied at a general level in the study of biochemical  structure and function. Prerequisite: CHEM 30284 and 40551.

60291/70291 Seminar: Recent Developments in Biochemistry (1)
Presentation and discussion of original papers from current literature. Participation by students and faculty.

60299 Thesis II (2)
Thesis students must continue registration until all degree requirements are met. S/U grading; IP permissible.Prerequisite: CHEM 60199.

62291/72291 Seminar: Biochemistry (1)
Students register once each year. Participation extends throughout the academic year. IP permissible.

 60253/70253 Biomacromolecular Structures(1)
Structure/function of motile processe3s in bacteria and eukaryotic cells; supermolecular structure and self-organization of proteins and nucleic acids in chromatin, spliceosomes, viruses and ribosomes. Prerequisite: special approval.

60254/70254 Biomembranes (3)
Biological membranes; composition, structure, dynamics and biogenesis; structure/function of protein mediated membrane transport. Prerequisite: special approval.

60297/70297 Advanced Biochemistry (2)
Course content is variable, each offering being concerned with a specific area of biochemistry. Examples are metabolism and regulation of the chemistry of proteins and other macromolecules. Lecture 2 hours weekly. Prerequisite: special approval.

60327/70327 Modern Inorganic Chemistry (3)
Synthesis, structure and reactivity of inorganic compounds, including transition metal and organometallic complexes. Prerequisite: CHEM 40362.

60337/70337 Inorganic Magnetic Spectroscopy (3)
Applications of magnetic resonance spectroscopic techniques (NMR, EPR and Mossbauer) in inorganic and organometallic compounds.

60347/70347 Chemical Crystallography (3)
Structure solution and refinement methods of X-ray diffraction data. Emphasis will be placed on single-crystal techniques. 

60391/70391 Seminar: Recent Developments in Inorganic Chemistry (1)
Presentation and discussion of current research papers in inorganic chemistry. Participation by students and faculty. IP permissible.

60471/70471 Advanced Organic Chemistry—Mechanistic Aspect (3)
Discussion of organic reaction mechanisms. Chemistry of reactive intermediates, aromaticity, addition/elimination, nucleophilic/electrophilic substitution, bonding theories and other fundamental topics governing organic reactions. Prerequisite: CHEM 30482.

60472/70472 Advanced Organic Chemistry—Synthetic Aspects (3)
Disconnection approach to organic synthesis. Modern methods for carbon bond formation and functional group interconversion, and their application to natural product synthesis. Prerequisite: CHEM 30482.

60473/70473 Stereoselective Organic Synthesis (3)
Modern methods of asymmetric synthesis; introduction to selected methods for stereoselective N-heterocycle synthesis; application of these methods in natural product synthesis. Prerequisite: CHEM 30482.

60541/70541 Advanced Physical Chemistry (3)
Covers basic materials of modern physical chemistry in two broad areas: thermodynamics and introductory quantum mechanics. Prerequisite: CHEM 50556.

60542/70542 Advanced Physical Chemistry (3)
Covers basic materials of modern physical chemistry in the area of application of wave mechanics to atomic structures, chemical bonding and reactivity. Prerequisite: CHEM 6/70541.

60543/70543 Statistical Thermodynamics (3)
Theory and applications of statistical thermodynamics and mechanics on non-interacting and interacting particles of real and model systems; gases, solutions, crystals, polymers; dielectric and magnetic phenomena. Prerequisite: CHEM 6/70542.

60563/70563 Quantum Chemistry (3)
Basic principles of quantum mechanics. Those aspects of theory of special interest to chemistry emphasized. Lecture 3 hours weekly. Prerequisite: CHEM 6/70541.

60591/70591 Seminar: Recent Developments in Physical Chemistry (1)
Presentation and discussion of original papers from current literature. IP permissible.

60894/70894 College Teaching of Chemistry (1)
Experience in teaching of chemistry at college level. S/U grading.

60898 Master's Research (1-15)
Research for master’s students. Credits earned may be applied toward degree if department approves. Repeat registration permitted. S/U grading; IP permissible.

61191/71191 Seminar: Problem Solving in Analytical Chemistry (1)
Discussion of recent chemical analysis methods, sample preparation and data handling, as well as practical student experience involving characterization of real samples. IP permissible.

61491/71491 Seminar: Problem Solving in Organic Chemistry (1)
Practical experience in solution of current problems of structure, synthesis and mechanism in organic chemistry. Participation extends throughout nine-month academic year. Repeat registration permitted. IP permissible.

62191/72191 Seminar: Analytical Chemistry (1)
Students register once each year. Participation extends throughout the academic year. IP permissible.

62391/72391 Seminar: Inorganic Chemistry (1)
Students register once each year. Participation extends throughout the academic year. IP permissible.

62491/72491 Seminar: Organic Chemistry (1)
Students register once each year. Participation extends throughout the academic year. IP permissible.

62591/72591 Seminar: Physical Chemistry (1)
Students register once each year. Participation extends throughout the academic year. IP permissible.

70195 Advanced Topics, Analytical (1-3)
Advanced topics in analytical chemistry. Repeat registration permitted. Prerequisite: special approval.

70295 Advanced Topics in Biochemistry (1-3)
Advanced topics in biochemistry. Repeat registration permitted. Prerequisite: special approval.

70395 Advanced Topics, Inorganic (1-3)
Advanced topics in inorganic chemistry. Repeat registration permitted. Prerequisite: special approval.

70495 Advanced Topics, Organic (1-3)
Advanced topics in organic chemistry. Repeat registration permitted. Prerequisite: special approval.

70595 Advanced Topics, Physical (1-3)
Advanced topics in physical chemistry. Repeat registration permitted. Prerequisite: special approval.

80199 Dissertation I (15)
Doctoral dissertation, for which registration in two semesters is required, first of which will be semester in which dissertation work is begun and continuing until the completion of 30 hours. S/U grading; IP permissible. Prerequisite: Admission to
candidacy.

80299 Dissertation (1 or 15)
Continuing registration required of doctoral students who have completed the initial 30 hours of dissertation and continuing until all degree requirements are met. S/U grading; IP permissible. Prerequisite: CHEM 80199.

80898 Research (1-15)
Research for doctoral students. Credits earned may be applied toward degree if department approves. Repeat registration permitted. S/U grading; IP permissible.